GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs9309473 | 1 | rs11899902 | chr2:73631564 | ALMS1P | chr2:73872046-73912692:+ | 0.33 | 4.87 | 1.65E-6 | Metabolite levels |
| BLCA | cis | rs9309473 | 1 | rs11901272 | chr2:73720444 | ALMS1P | chr2:73872046-73912692:+ | 0.4 | 5.94 | 6.54E-9 | Metabolite levels |
| BLCA | cis | rs9309473 | 1 | rs11903916 | chr2:73815328 | ALMS1P | chr2:73872046-73912692:+ | 0.38 | 5.65 | 3.06E-8 | Metabolite levels |
| BLCA | cis | rs10935120 | 1 | rs11919350 | chr3:134235970 | ANAPC13 | chr3:134196547-134204865:- | -0.5 | -7.88 | 3.42E-14 | Height |
| BLCA | cis | rs10935120 | 1 | rs11919350 | chr3:134235970 | CEP63 | chr3:134204575-134293852:+ | -0.24 | -4.04 | 6.44E-5 | Height |
| BLCA | cis | rs9815354 | 1 | rs11923562 | chr3:41760331 | ULK4 | chr3:41288091-42003660:- | 0.66 | 9.67 | 6.31E-20 | Diastolic blood pressure |
| BLCA | cis | rs10935120 | 1 | rs11927068 | chr3:134266321 | ANAPC13 | chr3:134196547-134204865:- | -0.5 | -7.97 | 1.89E-14 | Height |
| BLCA | cis | rs10935120 | 1 | rs11927068 | chr3:134266321 | CEP63 | chr3:134204575-134293852:+ | -0.24 | -4.09 | 5.33E-5 | Height |
| BLCA | cis | rs10935120 | 1 | rs11928499 | chr3:134232350 | ANAPC13 | chr3:134196547-134204865:- | -0.5 | -8 | 1.47E-14 | Height |
| BLCA | cis | rs10935120 | 1 | rs11928499 | chr3:134232350 | CEP63 | chr3:134204575-134293852:+ | -0.26 | -4.45 | 1.12E-5 | Height |
| BLCA | cis | rs9815354 | 1 | rs11928580 | chr3:41885722 | ULK4 | chr3:41288091-42003660:- | 0.64 | 9.83 | 1.74E-20 | Diastolic blood pressure |
| BLCA | cis | rs1109501 | 1 | rs11932207 | chr4:71330534 | AMTN | chr4:71384298-71398459:+ | 0.25 | 4.2 | 3.33E-5 | Alcoholism (heaviness of drinking) |
| BLCA | cis | rs28595532 | 1 | rs11938970 | chr4:119660152 | METTL14 | chr4:119606574-119632075:+ | -0.37 | -4.84 | 1.89E-6 | Cannabis dependence |
| BLCA | cis | rs7714584 | 1 | rs11950957 | chr5:150253914 | LOC134466 | chr5:150310000-150326146:- | 0.47 | 6.11 | 2.43E-9 | Crohn's disease |
| BLCA | cis | rs7714584 | 1 | rs11951694 | chr5:150254338 | LOC134466 | chr5:150310000-150326146:- | 0.48 | 6.23 | 1.22E-9 | Crohn's disease |